FGF23/FGFR4-mediated left ventricular hypertrophy is reversible

Left ventricular hypertrophy: is it really?

Background Patients with left ventricular hypertrophy (LVH), typically assessed by 2D echocardiography, are at a greater risk for heart failure and sudden cardiac death. An accurate diagnosis of LVH is essential to clinical evaluation and treatment. However, 2D echo has inferior spatial resolution and less than optimal measurement positioning, relative to cardiac MRI. This “real-world” study, b...

Left Ventricular Hypertrophy Familial Predisposition of Left Ventricular Hypertrophy

METHODS Echocardiographic and anthropometric measurements were performed in 2,293 individuals who participated in the echocardiographic substudies of population-based MONICA Augsburg surveys. In addition, a total of 319 siblings of survey participants with echocardiographic evidence of LVH were evaluated. The risk of these siblings to present with LVH or abnormal LV geometry was estimated by co...

Left ventricular hypertrophy.

Left Ventricular Hypertrophy

The vectorcardiographic diagnosis of left ventricular hypertrophy, using the Frank lead system, was evaluated in 93 autopsied male patients (70 with hypertrophy of the left ventricle and 23 without such hypertrophy). The criterion of the maximal QRS magnitude in the transverse plane greater than 2.2 mv below the age of 50 years and 1.8 mv at the age of 50 or more was positive in 61% of hypertro...

Physiological left ventricular hypertrophy.

Echocardiograms were recorded in 154 active athletes (from various sports) and 21 ex-athletes and compared with those in 40 normal control subjects (non-athletes). Diastolic cavity dimension and posterior wall and septal thickness were measured and left ventricular mass and the ratio of posterior wall thickness to cavity radius and of septum to posterior wall thickness calculated. As a group at...